研究：長期服抗B肝病毒藥 可逆轉肝硬化

[MK]

http://tw.news.yahoo.com/article/url/d/ ... 1ehwd.html
更新日期:2009/02/15 09:31
（中央社記者陳清芳台北15日電）肝指數正常的B肝帶原者突然爆肝，問題可能出在潛藏的肝硬化或肝損傷，醫界研究今天指出，長期服用抗B肝病毒藥物，可逆轉病情，使硬肝變軟、肝炎緩解。。


成大醫學院內科教授張定宗今天在香港舉行的亞太肝臟研究學會上，接受中央社記者越洋訪問相關跨國研究。他表示，包括17名台灣病患在內的57個B型肝炎病例，在服用Entecavir平均6年後，其中55人（96%）的壞死性肝炎指數、肝纖維化指數都是分數下降，顯示肝臟的組織型態好轉。


張定宗說，肝臟纖維化指數為0到6分，當達到5、6分時，就是肝硬化，許多臨床研究顯示，長期口服抗病毒藥物可以逆轉病情。然而，服藥愈久，病毒愈容易有抗藥性，目前只有少數藥物可單獨使用達6年，不必中途換藥或搭配其他藥物。


一般病人常在黃疸出現時，才驚覺肝臟發炎及硬化，張定宗解釋，因為肝臟是很能忍耐的器官，肝硬化、肝損傷潛藏在GOT、GPT等肝功能指數低於40正常值的假象下，實際上肝細胞受傷累累，一旦B肝病毒大肆活躍，肝炎來得又快又猛，或是肝癌迅速惡化。


為避免病患到必須換肝的地步，張定宗說，40歲以上、肝功能指數在40的邊緣、有肝癌家族病史的B肝帶原者，最好定期找醫師檢查是否肝硬化，而且在肝臟發炎初期，就應接受抗病毒藥物治療，讓肝臟有機會休養生息，再現生機。980215

[bruinhilde]

Liver Cirrhosis 可以reversible
真一個好消息
不過蠻懷疑的
那以後長疤的病人
可不可以也吃這個藥
疤痕就消失
哈哈哈
(樂奔) (樂奔) (樂奔) (樂奔)

[auricle]

肝指數正常的B肝帶原者去吃會不會破壞原來的和平共存讓病毒捉狂結果更糟 ? （阿飄）

[墨海]

我關心的是：長期服用誰要付錢？

昂貴的方法往往沒有實用性，還是落實在預防工作吧。

[xkuk]

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