【有Guts的公司】Xigris新試驗的結果未顯示出療效，禮來公司決定於全球主動撤離市場

[MK]

100禮來公司Xiris下架公告 DHCP Letter Chinese final.doc

(70 KiB) 已下載 106 次

Xigris Chinese PI.pdf

(278.75 KiB) 已下載 90 次

[image]

Xigris什麼藥? (咦)

[a4451a]

好像是治療DIC

[yingchi]

xigris (active protein C)
用在嚴重敗血症
使用上的條件有點嚴苛，
藥價很貴，所以聽說使用時，再怎麼符合健保條件，也會遭到核刪的命運......
不管怎樣，就是下市了

[sun yc]

SSC Surviving Sepsis Guidelines 2008
http://decode-medicine.blogspot.com/201 ... lines.html

Recombinant human activated protein C (rhAPC) (Xigirs)
Consider rhAPC in adult patients with sepsis-induced organ dysfunction with clinical assessment of high risk of death (APACHE II ≥ 25 or multiple organ failure) if there are no contraindications.

[gary]

厲害

[pinging]

這已經是禮來第二個治療敗血症的下價產品
前一個是E. coli的單株抗體
一開始我就對這兩種產品的研究報告頗多質疑
看來上市前試驗的品質大概多少受到主觀意志影響

[xkuk]

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[xkuk]

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