物理新發現 巴金森氏症盼有解

[MK]

http://tw.news.yahoo.com/article/url/d/ ... 2kmxz.html

更新日期:2011/01/11 14:45
（中央社記者林思宇台北11日電）熱門電影「愛情藥不藥」男主角著迷患有巴金森氏症的女主角，為了她四處求醫。中研院今天表示，找到蛋白質群集關鍵機制，類似巴金森氏症的神經退化性疾病治療，露出曙光。


日劇「一公升眼淚」的活潑可愛女主角「亞也」，在15歲時得了小腦脊髓萎縮症，25歲過世；「愛情藥不藥」女主角安海瑟威因巴金森氏症越來越嚴重，讓男主角傑克葛倫霍帶著她四處求醫，令人感動。


阿茲海默症、巴金森氏症、杭丁頓舞蹈症、小腦脊髓萎縮症及額顳葉退化症等神經退化性疾病，是因蛋白質在腦部發生群集現象，造成腦神經退化或死亡。目前醫學界對於這樣的疾病都無解，只能延緩發病，因此電影敘述到此類病症都是悲劇收場。


中研院物理所研究員胡進錕今天發表研究成果，有助於此類病症的了解。胡進錕表示，運用「晶格模型」研究影響群集速率的關鍵因素，發現可以從單獨一條蛋白質出現在群集型態的機率，來決定該蛋白質最容易產生群集現象的溫度。


胡進錕說，物理研究是要找到一般性的原理，未來將結合電腦模擬、解析分析和實驗數據，建立蛋白質群集現象的一般性理論，除溫度外，希望能找出其他如酸鹼度等影響蛋白質群集的因素，生醫界便可以因此研發藥物治療或是找出防治的方法。


胡進錕坦言，基礎研究經費有限，期盼更多經費投入，讓此項研究能在3至5年內完成。1000111

[squeak]

http://tw.news.yahoo.com/article/url/d/ ... 2kmxz.html

更新日期:2011/01/11 14:45
（中央社記者林思宇台北11日電）熱門電影「愛情藥不藥」男主角著迷患有巴金森氏症的女主角，為了她四處求醫。中研院今天表示，找到蛋白質群集關鍵機制，類似巴金森氏症的神經退化性疾病治療，露出曙光。


日劇「一公升眼淚」的活潑可愛女主角「亞也」，在15歲時得了小腦脊髓萎縮症，25歲過世；「愛情藥不藥」女主角安海瑟威因巴金森氏症越來越嚴重，讓男主角傑克葛倫霍帶著她四處求醫，令人感動。


阿茲海默症、巴金森氏症、杭丁頓舞蹈症、小腦脊髓萎縮症及額顳葉退化症等神經退化性疾病，是因蛋白質在腦部發生群集現象，造成腦神經退化或死亡。目前醫學界對於這樣的疾病都無解，只能延緩發病，因此電影敘述到此類病症都是悲劇收場。


中研院物理所研究員胡進錕今天發表研究成果，有助於此類病症的了解。胡進錕表示，運用「晶格模型」研究影響群集速率的關鍵因素，發現可以從單獨一條蛋白質出現在群集型態的機率，來決定該蛋白質最容易產生群集現象的溫度。


胡進錕說，物理研究是要找到一般性的原理，未來將結合電腦模擬、解析分析和實驗數據，建立蛋白質群集現象的一般性理論，除溫度外，希望能找出其他如酸鹼度等影響蛋白質群集的因素，生醫界便可以因此研發藥物治療或是找出防治的方法。


胡進錕坦言，基礎研究經費有限，期盼更多經費投入，讓此項研究能在3至5年內完成。1000111

腦內的組成大都是蛋白質，有發炎或退化，當然就都會黏在一起。除非是發明個藥可以逆反應蛋白質的變性反應，這不就是可以返老回童了？ (偽可愛)

[肉咖]

天山童姥 (眼汪汪)

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